DIGITAL QUANTIFICATION OF GENE EXPRESSION IN SEQUENTIAL BREAST CANCER BIOPSIES REVEALS ACTIVATION OF AN IMMUNE RESPONSE.

Advancements in molecular biology have unveiled multiple breast cancer promoting pathways and potential therapeutic targets.Large randomized clinical trials remain the ultimate means of validating therapeutic efficacy, but they require large cohorts of patients and are lengthy and costly.A useful approach is to conduct a window of opportunity study

The proliferation of Internet-of-Things (IoT) technology and its reliance on the license-free Industrial, Scientific, and Medical (ISM) bands have rendered radio spectrum scarce.The IoT can pata de avestruz botas nevertheless obtain great advantage from Cognitive Radio (CR) technology for efficient use of a spectrum, to be implemented in IEEE 802.1